diff --git a/package/python-setuptools/Config.in b/package/python-setuptools/Config.in
index 73368c1a49..d47f758750 100644
--- a/package/python-setuptools/Config.in
+++ b/package/python-setuptools/Config.in
@@ -2,7 +2,6 @@ config BR2_PACKAGE_PYTHON_SETUPTOOLS
 	bool "python-setuptools"
 	select BR2_PACKAGE_PYTHON3_PYEXPAT # runtime
 	select BR2_PACKAGE_PYTHON3_ZLIB # runtime
-	select BR2_PACKAGE_PYTHON_WHEEL # runtime
 	help
 	  Download, build, install, upgrade, and uninstall Python
 	  packages.