diff --git a/package/domoticz/domoticz.mk b/package/domoticz/domoticz.mk
index ab560ba05f..aeac0c65ef 100644
--- a/package/domoticz/domoticz.mk
+++ b/package/domoticz/domoticz.mk
@@ -33,6 +33,9 @@ DOMOTICZ_CONF_OPTS += \
 
 ifeq ($(BR2_PACKAGE_LIBUSB),y)
 DOMOTICZ_DEPENDENCIES += libusb
+DOMOTICZ_CONF_OPTS += -DWITH_LIBUSB=ON
+else
+DOMOTICZ_CONF_OPTS += -DWITH_LIBUSB=OFF
 endif
 
 ifeq ($(BR2_PACKAGE_OPENZWAVE),y)