diff --git a/package/python-setuptools/Config.in b/package/python-setuptools/Config.in
index 28228534f8..73368c1a49 100644
--- a/package/python-setuptools/Config.in
+++ b/package/python-setuptools/Config.in
@@ -1,7 +1,8 @@
 config BR2_PACKAGE_PYTHON_SETUPTOOLS
 	bool "python-setuptools"
-	select BR2_PACKAGE_PYTHON3_ZLIB # runtime
 	select BR2_PACKAGE_PYTHON3_PYEXPAT # runtime
+	select BR2_PACKAGE_PYTHON3_ZLIB # runtime
+	select BR2_PACKAGE_PYTHON_WHEEL # runtime
 	help
 	  Download, build, install, upgrade, and uninstall Python
 	  packages.
diff --git a/package/python-setuptools/python-setuptools.mk b/package/python-setuptools/python-setuptools.mk
index d957930455..39ead10f55 100644
--- a/package/python-setuptools/python-setuptools.mk
+++ b/package/python-setuptools/python-setuptools.mk
@@ -12,6 +12,7 @@ PYTHON_SETUPTOOLS_LICENSE_FILES = LICENSE
 PYTHON_SETUPTOOLS_CPE_ID_VENDOR = python
 PYTHON_SETUPTOOLS_CPE_ID_PRODUCT = setuptools
 PYTHON_SETUPTOOLS_SETUP_TYPE = pep517
+PYTHON_SETUPTOOLS_DEPENDENCIES = host-python-wheel
 HOST_PYTHON_SETUPTOOLS_DEPENDENCIES = host-python-wheel
 
 $(eval $(python-package))